Accelerated Kidney Aging in Diabetes Mellitus
نویسندگان
چکیده
منابع مشابه
Immunosuppressive Drugs and Kidney Post-transplant Diabetes Mellitus
Background: As the rate of renal transplantation increases, more immunosuppressive drugs such as cyclosporine A (CsA) are consumed, particularly during the early months following transplantation, leading to post-transplant diabetes mellitus (PTDM) which can cause death. Objective: The present study examined the role of CsA in causing PTDM and other effect...
متن کاملDiabetes Mellitus in the Transplanted Kidney
Diabetes mellitus (DM) is the most common cause of chronic kidney disease and end stage renal disease. New onset diabetes mellitus after transplant (NODAT) has been described in approximately 30% of non-diabetic kidney-transplant recipients many years post transplantation. DM in patients with kidney transplantation constitutes a major comorbidity, and has significant impact on the patients and ...
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Diabetes mellitus (DM) significantly increases the overall morbidity and mortality, particularly by elevating the cardiovascular risk. The kidneys are severely affected as well, partly as a result of intrarenal athero- and arteriosclerosis but also due to noninflammatory glomerular damage (diabetic nephropathy). DM is the most frequent cause of end-stage renal disease in our society. Acute kidn...
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Nach einer Einleitung und Diskussion tiber die Eingenschaften der diabetischen Krankheiten wurde ausflihrlich trber die Aetiologie und Pathophysiologie der Zuckerankheiten,insbesondere der Altersdiabetis,gesprochen.Nach der symptomalogie der Diabetis haben wir die ncueste Einteilung der Zuckerkrankheiten genannt und die Untcrsuchungsmethoden,die heute Uhlich sind,erwahnt;dazu wurden unsere M...
متن کاملAccelerated age-related browning of human collagen in diabetes mellitus.
The nonenzymatic glycosylation reaction that is accelerated in diabetes is the first step of the Maillard or nonenzymatic browning reaction that occurs in stored food. The glucose-protein adduct rearranges and dehydrates to form brown and fluorescent pigments, which can act as crosslinks, resulting in decreased protein solubility and altered mechanical properties. Evidence suggesting that this ...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2020
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2020/1234059